Elitek (Rasburicase) for Injection

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General Information

Elitek (Rasburicase) is indicated for use to prevent high blood levels of uric acid from occurring. It is in children with cancer who are about to receive cancer chemotherapy treatment. It is a type of cancer like lymphoma, leukemia, and solid malignant tumors.

As soon as chemotherapy is given, the cancer cells are being destroyed. It releases a large amount of uric acid into the bloodstream. This medication allows uric acid to more easily be removed from the body. It is by the kidneys.

 

How does Elitek (Rasburicase) work?

Elitek (Rasburicase) catalyzes enzymatic oxidation of poorly soluble uric acid into an inactive and more soluble metabolite (Allantoin). This medication works by breaking down uric acid so that the body can eliminate it.

 

Why use Elitek (Rasburicase)?

Elitek (Rasburicase) is in the class of medications called enzymes. This medication contains Rasburicase as an active ingredient. It is a tetrameric protein with identical subunits. This product is a sterile, white to off-white, and lyophilized powder intended for intravenous administration. This is supplied as 3ml and 10ml colorless and glass vials containing Rasburicase at a concentration of 1.5 mg/mL after reconstitution. The Food and Drug Administration (FDA) approved this medication.

 

How to use Elitek (Rasburicase)?

This medication is given by injection into a vein. It is usually given over 30 minutes or as directed by your doctor. It is given once a day for 5 days. Chemotherapy is usually started 4-24 hours after the first dose of this medication.

If you do not know how to use it, ask for the assistance of your doctor. Follow the instructions very carefully.

 

What are the side-effects of Elitek (Rasburicase)?

  • Nausea
  • Headache
  • Vomiting
  • Constipation
  • Stomach pain
  • Fever
  • Diarrhea
  • Anxiety
  • Mouth sores
  • Ulcer
  • Sore throat
  • Rash
  • Swelling in your hands or feet

Call your doctor bright away if these serious side effects happen:

  • Fever
  • Chills
  • Persistent sore throat
  • Weakness
  • Severe dizziness
  • Chest pain
  • Trouble breathing
  • Dark urine
  • Yellowing eyes and skin

Warnings and Precautions

  • This prescription should only be used when clearly needed during pregnancy. Discuss the risks and benefits of this drug with your doctor before using this medication.
  • Tell to your doctor if you are allergic to it or if you have any allergies. Tell also to your doctor if you have any medical history or any current medications.
  • Caution is advised when using this medication in children less than 2 years old. They may be more sensitive to the side effects of this drug.