Evista (Raloxifene Hydrochloride)

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General information

Evista (Raloxifene Hydrochloride) is used by women to prevent and treat bone loss. It is called osteoporosis, a type of condition that weakens bones. It also makes the bones fragile. It usually happens after menopause.

This medication may also lower the chance of getting invasive breast cancer. It is a type of breast cancer that usually happens after menopause.

How does Evista (Raloxifene hydrochloride) work?

Evista (Raloxifene Hydrochloride) binds to estrogen receptors. It results in activation of estrogenic pathways in some tissues (agonism). It also activates the blockade of estrogenic pathways. It is in other tissues called antagonism.

The activity of this drug depends on the extent of recruitment of co-activators. It also depends on co-repressors to estrogen receptor (ER) target gene pro-motors. This medication appears to act as an estrogen agonist in the bone. It decreases bone resorption and bone turnover. It increases bone mineral density and lessens fracture incidence.

Why use Evista (Raloxifene hydrochloride)?

Evista (Raloxifene Hydrochloride) is an estrogen agonist or antagonist. It is referred to as a selective estrogen receptor modulator (SERM).     This medication belongs to the benzothiophene class of compounds. This comes as a 60 mg tablet for oral use. The food and drug administration (FDA) approved this medication.

How to use Evista (Raloxifene hydrochloride)?

This is to be taken by mouth as directed by your doctor. It is usually taken once a day. You may take it with or without food. To help you remember, take it at the same time each day. The dosage is based on your condition and response. Take it exactly as it is prescribed.

Do not take more than the prescription. Do not also take it more often. You should not suddenly stop taking this drug without consulting your doctor.

What are the side-effects of Evista (Raloxifene hydrochloride)?

  • Headache
  • Increased sweating
  • Hot flashes
  • Dizziness
  • Nausea
  • Joint pain
  • Leg cramps or leg pain
  • Spinning sensation
  • Stomach pain
  • Stuffy or runny nose

If these side effects continue or worsen, call for medical help right away.

Warnings and precautions

  • Before taking this medication, tell your doctor if you have any medical history.
  • Inform your doctor if you are taking any other medicines.
  • If there is a sign of an allergic reaction, call your doctor right away.
  • If you are pregnant or breastfeeding women, consult your doctor first. Discuss the risks and benefits of this drug.
  • Keep this at a dry and clean place.