Gralise (Gabapentin)

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General Information

Gralise (Gabapentin) is indicated to relieve nerve pain following a painful rash. It is called shingles caused by herpes zoster infection. Shingles can occur anywhere in the body. It often appears as a single stripe of blisters that wraps around either left or the right side of your torso. It usually occurs in adults. This kind of condition is called postherpetic neuralgia.

How does Gralise (Gabapentin) work?

Gralise (Gabapentin) interacts with cortical neurons. It is at auxiliary subunits of voltage-sensitive calcium channels. This drug increases the synaptic concentration of GABA. It enhances the responses at non-synaptic sites in neuronal tissues. Through that, the release of monoamine neurotransmitter is reduced.

This medication structurally resembles the neurotransmitter gamma-aminobutyric acid (GABA). Neurotransmitters are drugs that nerves use to communicate with one another.

Why use Gralise (Gabapentin)?

Gralise (Gabapentin) belongs to the class of medications called anti-seizure. It is also called as anti-epileptic or anticonvulsant drugs. It comes as a tablet for oral use. Each tablet contains Gabapentin as an active ingredient. It is available in the strengths of 300 mg or 600 mg. The Food and Drug Administration (FDA) has approved this medication.

How to use Gralise (Gabapentin)?

Gralise (Gabapentin) is to be taken by mouth with a full glass of water. It is usually taken with your evening meal. Take each dose at regular intervals. Swallow the tablet as a whole. Do not chew or break it. To help you remember, take it at the same time every day.

During the first 2 weeks of the medication, your doctor may gradually increase your dose. Do not take it more often than it is prescribed. Your condition will not improve any faster. It will also increase your risk of side effects.

What are the side-effects of Gralise (Gabapentin)?

  • Vertigo
  • Dizziness
  • Drowsiness
  • Sleepiness
  • Tired feeling or weakness
  • Swelling of the extremities
  • Headache
  • Nausea
  • Diarrhea
  • Constipation
  • Dry mouth
  • Blurred vision
  • Back pain
  • Loss of balance or coordination

Warnings and Precautions

  • Before taking this drug, inform your doctor if you have any medical history. Tell also if you have any current medication or treatments.
  • This drug may contain an inactive ingredient that causes an allergic reaction. Inform your doctor if you have any allergies.
  • This may not be prescribed for pregnant or breastfeeding women. Discuss with your doctor the risks and benefits in case you need to use this medication.