Tibsovo (Ivosidenib)

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General Information

Tibsovo (Ivosidenib) is indicated for the treatment of acute myeloid leukemia (AML). It is a certain type of blood cell cancer. In which it is characterized by the rapid growth of abnormal cells that build up in the bone marrow. It also includes blood and interferes with normal blood cells. This medication helps your bone marrow develop normal blood cells. It is to help you also need fewer blood transfusions.

How does Tibsovo (Ivosidenib) work?

Tibsovo (Ivosidenib) increases the levels of 2-hydroxyglutarate in leukemia cells. In which it leads to an increased number of improperly differentiated white blood cells. R132H and R132C substitutions are the most common types of mutations of the IDH1 enzyme. This drug inhibits R132 substitutions in the IDH1 enzyme and counters the uncontrolled growth of leukemia cells.

Why use Tibsovo (Ivosidenib)?

Tibsovo (Ivosidenib) is available in 250 mg strength. It is supplied as film-coated tablets for oral use. This medication contains an active ingredient of Ivosidenib. It is an inhibitor of mutations of the IDH1 enzyme. This was approved by the U.S. Food and Drug Administration (FDA).

How to use Tibsovo (Ivosidenib)?

Tibsovo (Ivosidenib) is usually taken once a day. It is to be taken by mouth with a full glass of water. You may take each dose with or without food. Do not take this medication with a high-fat meal. Swallow the medicine as a whole. Do not break or chew it.  

The dosage is based on your condition and response. Remember to take it at the same time every day. Do not increase the dose without consulting your doctor. If you vomit after taking a dose, do not take another dose. Call your doctor right away.

What are the side-effects of Tibsovo (Ivosidenib)?

Common side effects:

  • Diarrhea
  • Joint pain
  • Shortness of breath
  • Nausea
  • Swelling
  • Rash
  • Fever
  • Fatigue
  • Constipation
  • Cough
  • Increased white blood cell count

If there are signs of an allergic reaction, call for medical assistance right away:

  • Hives
  • Difficulty breathing
  • Swelling of your lips, face, throat, or tongue

Warnings and Precautions

  • Tell to your doctor if you have any medical history or any other medical conditions.
  • Do not share this medication with others who have the same situation as yours. While you are using this treatment, do not drink alcohol.
  • Avoid driving or using machinery. Severe drowsiness or dizziness can cause falls or other accidents.
  • Keep this and all your medicines away from the reach of children.