Abacavir and Lamivudine

General Information

Abacavir and Lamivudine are used to lessen the amount of HIV infection in the body. It helps the immune system to work better. This medication is not a cure for HIV. This will lower your chance of getting HIV complications such as:

  • New infections
  • Cancer

This medication is always used in combination with other anti-HIV medicines that attack HIV in different ways. Taking Abacavir and Lamivudine with other HIV medications will help you live longer and healthier lives.

How do Abacavir and Lamivudine work?

Acquired immune deficiency syndrome (AIDS) is caused by infection with HIV. This virus invades cells of the immune system, specifically the white blood cells known as CD4 T-helper lymphocytes. These cells usually work to activate other cells in the immune system to fight infection. Since HIV kills CD4 T-helper cells, over time the body becomes less able to fight the virus. Once the virus is inside the CD4 T-cell it increases. Part of the process of viral multiplication includes the transformation of the virus genetic material, RNA to DNA. This is achieved by a compound essential to the virus, called reverse transcriptase. Reverse transcriptase is a compound known as an enzyme.

Abacavir and Lamivudine work by blocking the action of this enzyme. In that way, it interferes with the conversion of viral RNA into DNA. This stops the virus from growing.

Why use Abacavir and Lamivudine?

Abacavir and Lamivudine is the active ingredient of this product. This decreases the virus’s ability to reproduce and grow. This also prevents it from becoming resistant to treatment. Abacavir and Lamivudine are available in the strengths of 300 mg and 600 mg. The Food and Drug Administration (FDA) has already approved this medicine.

How to use Abacavir and Lamivudine?

This medication is to be taken by mouth. Take each dose with a full glass of water. It is usually taken once a day or as directed by your doctor. The dosage is based on your medical condition.

Remember to take it at the same time every day. It is very important that you take it exactly as it is prescribed. Do not take more often than the prescription. Do not suddenly stop the medication without consulting your doctor.

What are the side effects of Abacavir and Lamivudine?

  • Vomiting
  • Nausea
  • Mouth sores
  • Abdominal pain
  • Cough
  • Sore throat
  • Fatigue
  • Shortness of breath
  • Diarrhea
  • Headache
  • Feeling unwell
  • Muscle pain

Warnings and Precautions

  • Before taking the medication, tell your doctor if you are allergic to it. Tell also if you have any allergies.
  • Use this drug with caution in people 65 years of age and those with liver disease.
  • This is not recommended for those with a decreased kidney function.
  • Consult your doctor first if you are pregnant or breastfeeding women before taking a dose.