Cytotec (Misoprostol)

Cytotec (Misoprostol)

General Information

Cytotec (Misoprostol) is used to prevent stomach ulcers while you take NSAIDs (ibuprofen, naproxen, and aspirin). This is used especially if you are at risk of developing ulcers or have a history of ulcers. This medication helps to decrease your risk of serious ulcer complications such as bleeding. This will also protect your stomach lining by lowering the amount of acid that comes in contact with it. Cytotec (Misoprostol) may also be used in combination with another drug (mifepristone) to end a pregnancy or called abortion.

How does Cytotec (Misoprostol) work?

Cytotec (Misoprostol) is extensively absorbed and undergoes rapid desertification to its free acid. In which it is responsible for its clinical activity and unlike the parent compound, is detectable in plasma. The alpha side chain undergoes beta-oxidation and the beta side chain undergoes omega-oxidation. It is followed by reduction of the ketone to give prostaglandin E analogs. Prostaglandins are chemicals that are made within many organs of the body including the stomach. In the stomach, prostaglandins are believed to protect the inner lining of the stomach from the ulcer-producing effects of NSAIDs.


Why use Cytotec (Misoprostol)?

Cytotec (Misoprostol) is a synthetic or man-made prostaglandin E analog. Each tablet of Cytotec has 100mcg or 200mcg of misoprostol for oral administration. This medication was approved by the Food and Drug Administration (FDA) in 1988.


How to use Cytotec (Misoprostol)?

The dosage and dosing schedule is based on your condition and response.

If you are taking this for stomach ulcers, take it by mouth usually four times a day. It is to be taken after meals and at bedtime to minimize diarrhea.

If you are taking this medication for abortion, take it by mouth or exactly as directed by your doctor.

Follow your doctor’s prescription very carefully. Use this regularly in order to get the most benefit of it. Take it at the same time each day.

What are the side-effects of Cytotec (Misoprostol)?

  • Nausea
  • Stomach cramps
  • Constipation
  • Menstrual cramps
  • Increased or irregular menstruation
  • Diarrhea
  • Vomiting
  • Gas
  • Headache
  • Spotting

Call your doctor right away if these happen:

  • Severe on-going stomach discomfort or diarrhea
  • Dehydration symptoms (heavy sweating, hot and dry skin, being unable to urinate or feeling very thirsty or hot)

Warnings and Precautions

  • Let your doctor know if you have any medical history or current treatments.
  • This is not prescribed during pregnancy. If you are breastfeeding women, consult your doctor first.
  • Keep this medication away from the reach of children.