Dilaudid (Hydromorphone Hydrochloride) 

Dilaudid (Hydromorphone Hydrochloride)

General Information

Dilaudid (Hydromorphone Hydrochloride) is used to relieve severe ongoing pain due to cancer. This medication contains hydromorphone in a long-acting form.

Do not use the extended-release form of this medication to relieve pain that is mild or that will go away in a few days. This is not for occasional or ‘as needed’ use.


How does Dilaudid (Hydromorphone Hydrochloride) work?

Dilaudid (Hydromorphone Hydrochloride) is an opioid agonist that can bind to different types of opioid receptors. Its analgesic effect is suggested to be related to the effect on the mu-opioid receptors. It has been reported to also have a minor affinity for the delta and kappa receptors. On the other hand, it is known to act at the level of the medulla which allows it to depress the respiratory drive and suppress cough.

The onset of action of the immediate-release form of hydromorphone is achieved in 15-20 minutes. It also has a lasting effect for 3-4 hours while the extended-release form onset of action is of 6 hours lasting for about 13 hours.

Why use Dilaudid (Hydromorphone Hydrochloride)?

Dilaudid (Hydromorphone Hydrochloride) belongs to a class of drugs known as opioid (narcotic) analgesics. it also a hydrogenated ketone of morphine. It helps on how to change your body’s feels and respond to pain. This is available as tablets for oral administration with the strengths of 2mg, 4mg, and 8mg. The Food and Drug Administration (FDA) approved this medication.

How to use Dilaudid (Hydromorphone Hydrochloride)?

The recommended dosage for this treatment is based on your condition and response.

This is to be taken by mouth with a full glass of water. It is usually taken once a day at the same time each day. You may take it with or without food. if you have nausea, it may help to take it with food.

What are the side-effects of Dilaudid (Hydromorphone Hydrochloride)?

  • Itching
  • Flushing (warmth, redness, or tingling of skin)
  • Nausea
  • Sweating
  • Constipation
  • Vomiting
  • Diarrhea
  • Dizziness
  • Stomach pain
  • Double or blurred vision
  • Headache
  • Insomnia (sleep problems)
  • Dry mouth
  • Drowsiness
  • Strange dreams

Warnings and Precautions

  • Before taking this drug, discuss with your doctor the risks and benefits.
  • Let your doctor know if you are allergic to it or if you have any allergies.
  • Avoid alcoholic beverages. Avoid also driving or using any machinery. This drug may make you feel dizzy or drowsy.
  • Keep this far from moisture and heat.