Fulyzaq (Crofelemer) is indicated to relieve symptoms of diarrhea in HIV/AIDS patients. It is for those who are taking medicines to treat HIV infection. This medication may lessen the number of watery stools you have. It may also help you better tolerate your HIV medications.
This drug is not be used to treat diarrhea caused by infections.
How does Fulyzaq (Crofelemer) work?
Fulyzaq (Crofelemer) is an inhibitor of the cystic fibrosis transmembrane regulator chloride channel (CFTR). It is as evidenced by its activity on cell cultures, single CFTR channels, and single cell patch clamps. It also includes the elaboration of mouse intestinal fluid secretion.
This medication also inhibits calcium-activated chloride channels which in combination with CFTR. Those are expressed on the luminal side of intestinal cells. The inhibition of both of these channels prevents water loss from diarrhea by inhibiting chloride secretion. It prevents water and minerals from entering into the intestines. That it causes the stools to be more solid.
Why use Fulyzaq (Crofelemer)?
Fulyzaq (Crofelemer) is in the form of delayed-release tablets. It is an enteric-coated drug product for oral use. It has 125 mg of Crofelemer which is a botanical drug substance. It is the active ingredient of this drug. The Food and Drug Administration (FDA) has approved this medication.
How to use Fulyzaq (Crofelemer)?
The recommended dosage is based on your medical condition and response. It is important to take it exactly as it is prescribed.
It is to be taken by mouth with a full glass of water. It is usually taken twice a day. do not chew or crush the tablet. It should be swallowed as a whole. Remember to take it at the same time every day.
What are the side-effects of Fulyzaq (Crofelemer)?
- Muscle pain
- Stuffy or runny nose
- Back pain
- Joint pain
- Urinary tract infection
- Upper respiratory tract infections
If these side effects continue or get worse, call your doctor right away.
Warnings and Precautions
- Before taking this drug, tell your doctor if you are allergic to it. Tell also if you have any medical history or current medications.
- This may not be recommended for pregnant or breastfeeding women. Consult your doctor first before taking it.
- Do not share this with others even if they have the same symptoms as yours.
- Keep this at a dry and clean place away from moisture and heat.