Glucotrol (Glipizide)

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General Information

Glucotrol (Glipizide) is used in people with type 2 diabetes to control high blood sugar. It is used along with a proper diet and exercise program. It may also be used with other diabetes medication.

It helps prevent nerve problems and kidney damage when you control high blood sugar. It may also prevent loss of limbs, blindness, and sexual function problems. Appropriate control of diabetes may also lessen your risk of stroke or heart attack.

How does Glucotrol (Glipizide) work?

Insulin is a hormone that is produced in the pancreas. That when released into the blood, it causes cells in the body to remove sugar from the blood. It decreases the formation of glucose by the liver. Those people with type 2 diabetes have high glucose levels in their blood. It is because the cells in their bodies are resistant to the glucose-removing effect of the insulin. The liver creates too much glucose.

In addition, in type 2 diabetes the pancreas is unable to create the increased amounts of insulin that are necessary to overcome the resistance. This drug reduces blood sugar by stimulating the pancreas to produce more insulin.

Why use Glucotrol (Glipizide)?

Glucotrol (Glipizide) belongs to the class of medications called sulfonylureas. It comes as a tablet for oral use. It is available in 5 mg and 10g strengths. It contains an active ingredient of Glipizide. The Food and Drug Administration (FDA) has approved this drug in 1984.

How to use Glucotrol (Glipizide)?

This medication is to be taken by mouth usually once a day. It is taken 30 minutes before breakfast or the first meal of the day. For some patients, especially those taking higher doses, the doctor may prescribe to take it twice a day.

The recommended dosage is based on your medical condition and response to it. Remember to take it at the same time every day. Do not take it more than the prescription.

What are the side-effects of Glucotrol (Glipizide)?

  • Constipation
  • Diarrhea
  • Vomiting
  • Nausea
  • Loss of appetite
  • Upset stomach
  • Weight gain
  • Gas
  • Drowsiness
  • Dizziness
  • Skin changes (hives, rash, itching, redness, or blisters)

Warnings and Precautions

  • Inform your doctor if you have any medical history or current medication/treatments.
  • This drug may have an inactive ingredient that causes an allergic reaction. Tell your doctor if you have any allergies.
  • Call for medical help right away if there are any signs of an overdose.
  • Do not double the dose. If you missed a dose, take it as soon as you remember it. If it’s already time for your next dose, never mind the missed dose.