Lodine (Etodolac)

General Information

Lodine (Etodolac) is indicated to relieve pain from various conditions. It may also be used to lessen swelling, pain, and joint stiffness from arthritis.

Be careful to consider the potential risks and benefits of this capsule. And other treatment options before deciding to use this. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals.

How does Lodine (Etodolac) work?

The anti-inflammatory effects of this drug result from inhibition of the enzyme cyclooxygenase (COX). This declines the synthesis of peripheral prostaglandins involved in mediating inflammation. This medication binds to the upper portion of the COX enzyme. It is an active site and it prevents its substrate and arachidonic acid from entering the active site.

This was previously thought to be a non-selective COX inhibitor. But it is now known to be 5 to 50 times more selective for COX-2 than COX-1.

An Antipyresis may occur by central action on the hypothalamus. It may result in peripheral dilation, subsequent heat loss, and increased cutaneous blood flow.


Why use Lodine (Etodolac)?

Lodine (Etodolac) is an anti-inflammatory agent. It contains analgesic and antipyretic properties. This medication is also known as a nonsteroidal anti-inflammatory drug (NSAID). This comes as a capsule for oral use. Each capsule has Etodolac as an active ingredient. This is available in the strength of 300 mg. The Food and Drug Administration (FDA) approved this medication.


How to use Lodine (Etodolac)?

The recommended dosage is based on your medical condition and response.

This is to be taken by mouth with a full glass of water. It is usually taken 2 to 3 times a day. After taking this drug, do not lie down for at least 10 minutes. Take this medication with food, milk, or an antacid to prevent stomach upset.

Follow the prescription of your doctor very carefully to avoid some complications.

What are the side effects of Lodine (Etodolac)?

  • Diarrhea
  • Vomiting
  • Upset stomach
  • Constipation
  • Heartburn
  • Stomach pain
  • Gas bloating
  • Headache
  • Dizziness
  • Sore throat
  • Nervousness
  • Rash
  • Stuffy nose
  • Blurred vision
  • Ringing in the ears


Warnings and Precautions

  • Before taking this drug, discuss with your doctor the risks and benefits. Tell to your doctor if you are pregnant or breastfeeding women.
  • Inform your doctor if you are allergic to it or if you have any allergies.
  • Tell also your doctor if you have any medical history or current medications/treatments.
  • Keep this away from heat and moisture.
  • Store this drug at room temperature.