General Information

Mepolizumab is indicated to control and prevent symptoms caused by asthma such as:

  • Wheezing
  • Shortness of breath

Controlling symptoms of asthma helps you do your normal activities. This also decreases the time lost from work or school. Mepolizumab may also be used to treat eosinophilic granulomatosis with polyangiitis (EGPA). This medication helps prevent and control symptoms like:

  • Runny nose
  • Shortness of breath
  • Wheezing
  • Facial pain

How does Mepolizumab work?

Mepolizumab works by lessening the swelling or inflammation of the airways in the lungs. It is to make breathing easier. This also works by reducing the swelling or inflammation of the blood vessels. Mepolizumab may as well decrease the amount of certain white blood cells that may cause the disease.

Why use Mepolizumab?

Mepolizumab is in the class of medications called monoclonal antibodies. This blocks the action of a certain natural substance in the body that causes asthma. This is a prescription approved by the Food and Drug Administration (FDA). Mepolizumab is supplied as a sterile, white to off-white, preservative-free, and lyophilized powder for subcutaneous injection. Each single-dose vial delivers 100 mg of Mepolizumab.

How to use Mepolizumab?

The recommended dosage for this medication is based on your condition and response. You must take this exactly as it is prescribed. Do not take in a larger or smaller amount. It may worsen or may cause another condition.

Mepolizumab is used by injection under the skin into the upper arm, abdomen, or thigh. This is used as directed by your doctor usually once every 4 weeks. Do not shake the drug. Clean the injection site with rubbing alcohol before injecting each dose. To lessen injury under the skin, change the injection site each time to lessen injury under the skin. Use this medication regularly for best results.

What are the side effects of Mepolizumab?

  • Nausea
  • Skin rash
  • Sweating
  • Joint pain
  • Loss of appetite
  • Cough
  • Diarrhea
  • Back pain
  • Vomiting
  • Trouble sleeping
  • Stomach pain
  • Dizziness
  • Noisy breathing
  • Confusion

Warnings and Precautions

  • Do not inject into areas of skin that are tender, red, bruised, or hard.
  • Let your doctor know if your condition gets worse or does not improve.
  • This should be used by pregnant and breastfeeding women.
  • You should not use this if you are allergic to it.
  • Tell your doctor if you have any medical history or current medications.
  • Keep this at room temperature far from the reach of children.