Tirofiban HCL

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Where is Tirofiban HCL used?

Tirofiban HCL is used to lessen the rate of thrombotic cardiovascular proceedings. It is refractory ischemia cardiac, an endpoint of death, or combined myocardial infarction procedure. This is usually used in individuals with non-ST elevation acute coronary syndrome.

This drug is an isosmotic, non-preserved, and sterile premixed injection. It also has sodium chloride for tonicity adjustment. Tirofiban HCLis a non-peptide antagonist of the platelet GP IIb/IIIa receptor that prevents the accumulation of platelets. This is supplied as a sterile solution in water for intravenous use. The Food and Drug Administration (FDA) has approved this medication.

How does Tirofiban HCL work?

Tirofiban HCL is a changeable antagonist of fibrinogen binding to the GP IIb/IIIa receptor. It is the central platelet surface receptor involved in platelet accumulation. When given intravenously, this prevents ex vivo platelet aggregation in a dose. It also inhibits in a concentration-dependent manner.

This medication prevents platelet function as established by its capability to prevent:

  • Patients with coronary artery disease
  • Prolong bleeding time in healthy subjects
  • Ex vivo adenosine phosphate-induced platelet accumulation

The time development of inhibition counterparts the plasma absorption profile of the medicine.

How is Tirofiban HCL given?

The dosage of this medication is based on the medical condition and weight as well as the first response to the drug. This medication is given by injection slowly into a vein over many hours by a health care professional or given as directed by your doctor. It is usually given for at least 48 hours, especially for unstable angina or those who have had a heart attack. This medicine is given by injection. To avoid complications, do not double the given dosage.

After your procedure, you will need to lie very still with your head up slightly if you have certain heart procedures to open up the blood vessels in your heart. The tube used is commonly placed near the groin. To avoid bleeding from the tube area, keep the leg straight. Pressure will be applied to the area as well. You will not be allowed out of bed for several hours after the procedure.

What are the possible side effects of Tirofiban HCL?

  • Nausea
  • Fever
  • Bleeding
  • Dizziness
  • Headache
  • Swelling or pain at the injection site
  • Signs of a severe allergic reaction (hives, trouble breathing, swelling)
  • Bleeding from any wounds
  • Decreased in cell platelets

If these persist or get worse, call your doctor or medical assistance right away.

What are the precautions in using Tirofiban HCL?

  • Before using this medication, inform your doctor if you have current medications, any allergies, or medical history.
  • This is not prescribed for pregnant women. If you are breastfeeding women, you should stop it while having this treatment. You may continue after 24 hours after treatment has been stopped.
  • If you have any infections at the injection site, consult your doctor.
  • Do not change the prescribed dosage unless your doctor tells you to do so.
  • Do not use this drug for any other treatment.
  • Keep this away from the reach of children.